Chrysin attenuates inflammatory and metabolic disorder indices in aged male rat
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چکیده
منابع مشابه
L-methionine attenuates gentamicin nephrotoxicity in male Wistar rat: pathological and biochemical findings
The clinical uses of gentamicin have so far been restricted due to nephrotoxicity and ototoxicity. The exact mechanism of nephrotoxicity is still unknown; however, it appears that free radicals may be involved. Methionine has previously been shown to alleviate oxidative stress involved in ototoxicity due to its antioxidant properties. Therefore, the effect of methionine supplementation on the g...
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Objective(s):Acute kidney injury (AKI), a syndrome characterized by decreased glomerular filtration, occurs in every 1 of 5 hospitalized patients. Renal ischemia-reperfusion, one of the main causes of AKI, is of particular importance in the setting of kidney transplantation. Materials and Methods: Sixty male rats were divided into four groups including control, nephrectomy, sham surgery and re...
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Aging is associated with a decline in cardiac function. Exercise intervention has been suggested as a way to improve this decrement. Age-related decline in cardiac function is associated with decreases in fatty acid oxidation, mitochondrial function, and AMP-activated protein kinase (AMPK) activity. The molecular mechanisms involved with age-related changes in mitochondrial function and substra...
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متن کاملl-methionine attenuates gentamicin nephrotoxicity in male wistar rat: pathological and biochemical findings
the clinical uses of gentamicin have so far been restricted due to nephrotoxicity and ototoxicity. the exact mechanism of nephrotoxicity is still unknown; however, it appears that free radicals may be involved. methionine has previously been shown to alleviate oxidative stress involved in ototoxicity due to its antioxidant properties. therefore, the effect of methionine supplementation on the g...
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ژورنال
عنوان ژورنال: Biomedicine & Pharmacotherapy
سال: 2019
ISSN: 0753-3322
DOI: 10.1016/j.biopha.2018.10.059